Health Library Antihistamines for VertigoFrom Healthwise

The exact way that an antihistamine reduces vertigo is not known. Some of these antihistamines may also reduce nausea and vomiting.

Dimenhydrinate and promethazine are available as an injection, suppository, or tablet. Diphenhydramine is available as an injection or a tablet.

Antihistamines may be prescribed to control vertigo that is caused by inner ear problems, including Ménière's disease, inflammation of the inner ear ( labyrinthitis), benign paroxysmal positional vertigo (BPPV), and inflammation of the nerve to the inner ear ( vestibular neuronitis). Dimenhydrinate may be used to prevent and control nausea and vomiting caused by chemotherapy.

Antihistamines control vertigo well in some people and not at all in other people. It may be necessary to try several antihistamines to find one that works for you.

The most commonly reported side effect is drowsiness. Do not use a medication that makes you drowsy if you will be driving or operating dangerous equipment.

Antihistamines may also cause blurred vision or a dry mouth.

See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)

Most antihistamines should be avoided during early pregnancy, if possible.

Complete the new medication information form (PDF)(What is a PDF document?) to help you understand this medication.

Author:	Kathe Gallagher, MSW	Last Updated: January 29, 2007
Medical Review:	Anne C. Poinier, MD - Internal Medicine Barrie J. Hurwitz, MD - Neurology
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