C. Bruce Malone was born in Nashville, Tennessee. He graduated from Harvard College and Duke University School of Medicine. He completed his internship and his residency in orthopedic surgery at Case Western Reserve University Hospitals in Cleveland, Ohio. He was a major in the United States Air Force Medical Corps. He joined the Austin Bone and Joint Clinic in 1977. He is board certified by the American Board of Orthopedic Surgery, and is a fellow in the American Academy of Orthopedic Surgeons, a member of the Texas Orthopedic Association, and the TMA.
He has been the chief of orthopedics, president of the medical staff, and on the Board of Governors of St. David's Health Care Partnership. He has been the president of the Travis County Medical Society, a delegate to the AMA from Texas, and is currently a TMA delegate from Travis County. He is on the Texas Board of BC/BS and the Texas Medical Foundation. He was listed on the "Best Doctors" list in Austin Magazine.
His special interests are in major joint reconstruction and lumbar spine surgery. He is married and has two children. His outside interests include hunting, skiing, and golfing.